I'm Going To Call These Two Locks:
Murray State +5.5 vs. Marquette
Murray State should be favored in this game. Some of the best guard play in the country, a swarming defense and the most over ranked/seeded team in the country is the recipe for a win. Marquette is not the trash team Colorado State was, but they will not win, much less cover 5 and a half points.
New Mexico +1 vs. Louisville
Really not a fan of Louisville. Peyton Siva has matured into a dependable point guard, and I like Kyle Kuric because he is the rare athletic white wing, but they just don't have the firepower of a usual Rick Pitino outfit. New Mexico is strong down low (Drew Gordon a future NBA guy) and Kendall Williams can put Siva on lockdown like he did Casper Ware in their first round matchup.
Riskier Territory
Gonzaga +7.5
The Zags are long and athletic down low, which will give the most overrated player in college basketball trouble. The issue in this game will not be controlling dough-boy Sullinger, it will come down to the Zags' inexperienced guards being strong with the ball against Ohio State's pressure. I like Ohio State to win, but Gonzaga should keep it close.
Vanderbilt +1 vs. Wisconsin
Jeffrey Taylor is an elite athlete and his size should give Jordan Taylor fits. Taylor is the key to the Wisconsin attack and with Ezeli down low and Jenkins firing away from the outsides, the Commodores have too much firepower for the Badgers to keep up with.