So far in 2012, SMU has lost 59-24 to Baylor and 48-3 to Texas A&M. The odds makers don't expect that pattern to change when they host TCU, another former SWC opponent who has gone on to bigger things, on Saturday.
The Frogs, who have moved up to No. 15 in the polls, have looked strong in their first season as a member of the Big 12. They're currently favored to beat the Mustangs by -16.5 points in Dallas.
SMU's hapless defense has made Nick Florence and Johnny Manziel look like stars already this season, so Casey Pachall could be in line for another huge game on Saturday.
The TCU QB has put up absolutely crazy numbers in 2012: 76.1% completion percentage, 847 yards, 8 TD's and 1 INT.
Garrett Gilbert, the highly-touted Texas transfer, hasn't been nearly as effective in June Jones' spread offense, completing 52.8% of his passes for 694 yards, 3 TD's and 4 INT's.
There's a lot of bad blood in this rivalry, especially after the Mustangs' huge upset in 2011, which led to a post-game tirade by the normally mild-mannered Gary Patterson.
The over/under for this game is 54½, a number which could very well be made up of only TCU scores on Saturday.
For more coverage of the game, stay tuned to the SB Nation Dallas StoryStream as well as Frogs O'War.