Baylor, the NCAA's most prolific passing team averaging 417 yards per game through the air, will clash with Gary Patterson's defense that is giving up just 13.2 points per game, which is good enough for 10th in the nation.
Senior quarterback Nick Florence has put up 1,585 yards this season and completed 64 percent of his passes. He also has 16 touchdowns and five interceptions for Baylor.
The Bears (3-1, 0-1 Big 12) are coming off a bye week following a 70-63 loss in a shootout with West Virginia two weeks ago.
Meanwhile, the Horned Frogs (4-1, 1-1 Big 12) will look to regroup after falling to Iowa State 37-23 last week. That loss knocked TCU from the top-25 polls, and it didn't help that starting quarterback Casey Pachall missed the game after being suspended indefinitely following an arrest for driving while intoxicated. Pachall's status is expected to be updated by Patterson on Tuesday, according to CBS Sports.