In their first ever game as members of the Big 12, the No. 16 TCU Horned Frogs are heavy favorites to win their debut, when they head to Lawrence to take on the Kansas Jayhawks.

With a 56-0 win over Grambling State in their opener, TCU has yet to see a true test, and most would argue that the Jayhawks will not be the ones to provide that. Charlie Weis' squad certainly ought to provide a tougher challenge than Grambling State.

In the first season for the Jayhawks with Charlie Weis at the helm, Kansas got out to a decent start with a 31-17 win over South Dakota State, but a 25-24 loss to Rice in the subsequent week spoiled the fun. Now Kansas enters as three-score underdogs for Saturday's game.

Game time/date: 11:00 a.m. CT, Saturday, Sept. 15

Location: Memorial Stadium, Lawrence, KS

TV: FX

Odds: TCU opened as 22-point favorites and are currently 21-point favorites.

Matchup History: TCU leads 16-8-4

For more coverage of TCU, check out Frogs O'War, while Rock Chalk Talk has all the latest news and notes on Kansas.