The Dallas Cowboys head to Philadelphia for the biggest game of their season as +3.5 underdogs.

Both teams have stumbled out of the gate early, with Dallas tied for second in the NFC East at 3-3 and Philadelphia in last at 2-4. A win for either would be a huge boost in a crowded division, while a loss would seriously jeopardize a playoff berth for both.

For the Cowboys, the emergence of a running game, in the form of Oklahoma rookie DeMarco Murray, is the best news to come out of their 34-7 drubbing of the St. Louis Rams last week.

Philadelphia has struggled against the run this year, giving up 123.8 yards a game, 23rd in the NFL. A ground game also has the added benefit of keeping the Eagles' explosive offense off the field.

The Eagles, meanwhile, are coming off a bye week, and head coach Andy Reid is 12-0 in his time in Philadelphia in the game after the bye. They'll be looking to exploit the Cowboys secondary with their duo of big-play receivers in DeSean Jackson and Jeremy Maclin.

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