The 2012 NFL season kicks off on Wednesday night, when the Dallas Cowboys head to New Jersey to take on the New York Giants. As such, fantasy football season also officially begins -- even though there's just one game on Wednesday.
Since we don't know a whole lot about what either the Cowboys or Giants will be like this year, you're best off starting all of the major skill players in the game.
Tony Romo is definitely a must-start, despite facing a defense with an excellent pass rush. Romo has top 10 QB potential this year, and if the Cowboys stay healthy, he could be a top five fantasy quarterback.
Wide receivers Miles Austin and Dez Bryant also need to be started as well. Both have WR1 potential, and at worst, are WR2s on Wednesday night. If you've got two better receivers than either of them, then you'll probably be using your flex play on either Cowboy receiver.
DeMarco Murray is also a must-start.
Jason Witten, meanwhile, can be safely benched for Week 1. Witten has been listed as doubtful for Wednesday night's game.
On the opposite side of things, Eli Manning can safely be started, as can Victor Cruz. Hakeem Nicks is a bit risky, though, with his foot problem. Still, I'd probably start him against the Cowboys, until Dallas' secondary proves that they can stop the pass.